|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells.
|
29898774 |
2018 |
|
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Entrectinib's activity against both ALK and TRK proteins suggests a possible role in NB treatment, and it is currently under investigation in both pediatric and adult oncology patients.
|
30425456 |
2018 |
|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Gene expression of TRK neurotrophin receptors in advanced neuroblastomas in Singapore--a pilot study.
|
21728718 |
2011 |
|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Expression of Trk receptors is an important prognostic factor in neuroblastoma (NB) and other cancers.
|
19363525 |
2009 |
|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Expression of Trk receptors has been implicated in the pathogenesis and prognosis of embryonal tumors, including neuroblastoma, nephroblastoma, and medulloblastoma.
|
17973327 |
2008 |
|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, we used the SH-SY5Y human neuroblastoma cell line ectopically expressing either TrkA or TrkB as a model system to analyze the impact of Trk receptor expression on NHEJ-mediated DSB repair.
|
18678285 |
2008 |
|
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Because the Shc family proteins (ShcA, ShcB, and ShcC) are adaptors for various receptors, including Trk receptors, and are regulators of neuronal cell development, we speculated that they may play a role in neuroblastoma.
|
15867224 |
2005 |
|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Neurotrophins (NTs) bind to two different classes of cell surface receptors, Trk receptor tyrosine kinases and p75NTR, both of which are expressed by neuroblastoma cells.
|
15015775 |
2004 |
|
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Little is known about the signal transduction pathways of TRK family receptors in neuroblastoma (NB) cells.
|
11223544 |
2001 |
|
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Indeed, there is increasing evidence that TRK genes play an important role in the biology and clinical behavior of neuroblastomas, tumors of the peripheral nervous system.
|
9049830 |
1997 |
|
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis.
|
8481906 |
1993 |
|
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In addition, we tested two primary neuroblastomas that expressed TRK for responsiveness to nerve growth factor.
|
8441429 |
1993 |