Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
Median TPO antibody titer was not different between those with and without thyroid IRAEs but was higher in those with overt as compared to subclinical hypothyroidism (5 vs. 0.3 IU/mL, p=0.003) and those prescribed thyroid hormone replacement as compared to observation (5.5 vs. 0.3, p=0.008).
|
31813343 |
2020 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
Subclinical hypothyroidism was more likely in thyroid peroxidase positive pregnant women (OR=2.56).
|
31724489 |
2020 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
According to the TSH reference range recommended by American Thyroid Association (ATA), the prevalence of subclinical hypothyroidism, subclinical hyperthyroidism, hyperthyroidism, hypothyroxinemia, and thyroid peroxidase antibody-positive were 12.42%, 0.50%, 0.99%, 1.61%, and 11.80%, respectively, prevalence according to the trimester-specific reference range were 1.99%, 0.25%, 1.61%, 0.37%, and 1.61%, respectively, which showed elevated hypothyroxinemia incidence and declined incidence of subclinical hypothyroidism and hyperthyroidism.Trimester-specific reference range varied from that of ATA's recommendation, influencing the diagnosis, and treatment of pregnant thyroid disorders.
|
30681614 |
2019 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
The study population included 47 045 pregnant women (mean age, 29 years; median gestational age at blood sampling, 12.9 weeks), of whom 1234 (3.1%) had subclinical hypothyroidism (increased thyrotropin concentration with normal FT4 concentration), 904 (2.2%) had isolated hypothyroxinemia (decreased FT4 concentration with normal thyrotropin concentration), and 3043 (7.5%) were TPO antibody positive; 2357 (5.0%) had a preterm birth.
|
31429897 |
2019 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
Twelve infertile women with thyroglobulin antibody (TGAb) and thyroid peroxidase antibody (TPOAb)-negative nongoitrous SH were referred to our department of endocrinology between September 2007 and September 2015.
|
30568076 |
2019 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
Currently, there is no consensus on universal thyroid screening and levothyroxine (LT4) treatment of pregnant women with subclinical hypothyroidism (SCH) who are negative for thyroid peroxidase antibody (TPOAb-).
|
29126290 |
2018 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
Subclinical hypothyroidism at 12 weeks occurred in up to 60% of class 3 women and was accompanied by elevated thyroid peroxidase antibodies (TPO-Ab) titers (50%) and a parental history of thyroid dysfunction (23%).
|
29846629 |
2018 |
Subclinical hypothyroidism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between TPO Asn698Thr and Thr725Pro gene polymorphisms and serum anti-TPO levels in Iranian patients with subclinical hypothyroidism.
|
28500830 |
2017 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this research was to determine the optimal thyroid-stimulating hormone cut-off point to screen for subclinical hypothyroidism in the first trimester of gestation in a population of our clinical area and to determine the diagnostic value of this screening test for detecting anti-thyroid peroxidase antibodies.
|
29273014 |
2017 |
Subclinical hypothyroidism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The 2.5th and 97.5th percentiles of TSH and fT4 during pregnancy in TPO-Ab-negative (<35 kU/L) women were used to define euthyroid women and those with overt (clinical) and subclinical hypothyroidism.
|
28746798 |
2017 |
Subclinical hypothyroidism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Final diagnosis in children with subclinical hypothyroidism and mutation analysis of the thyroid peroxidase gene (TPO).
|
19960894 |
2009 |
Subclinical hypothyroidism
|
0.100 |
Biomarker
|
disease |
BEFREE |
After exclusion of patients with subclinical hypothyroidism and/or TPO antibodies (n = 16), higher serum TSH significantly predicted response (response rate per tertile from low to high TSH: 36%, 42%, and 67%).
|
16728541 |
2006 |