TPO, thyroid peroxidase, 7173

N. diseases: 306; N. variants: 47
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE A diagnosis of autoimmune thyroiditis (AT) in thyrotoxic phase was made on the basis of clinical presentation and presence of anti-TPO antibodies and reduced uptake in thyroid (technetium) scintigraphy. 30128632 2019
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE The prevalence of anti thyroperoxidase (TPO) was significantly increased in the autoimmune thyroiditis (AIT). 30807792 2019
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 AlteredExpression disease BEFREE This clinical trial was designed to investigate the impact of Se and vitamin C supplementation on antithyroid peroxidase antibody (TPO-Ab) level in patients with AIT. 30182359 2019
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE This study included 933 patients with thyroid peroxidase antibodies (anti-TPO-Ab) ≥34 kIU/l, including most patients with clear AIT due to a concurrent sonographic evidence of reduced echogenicity. 31766063 2019
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE The aim of the present study was to explore the effect of Se on thyroid peroxidase antibody (TPOAb) titers in patients with AIT and to analyze a potential impact of the genetic background on the effect of Se supplementation Methods Randomized, placebo-controlled, double-blind trial. 30398407 2018
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 GeneticVariation disease BEFREE We experienced a 6-year-old case of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) with subsequent development autoimmune thyroiditis (Hashimoto's thyroiditis), type 1 diabetes with antithyroglobulin, thyroid peroxidase, insulinoma-associated antigen and anti-insulin antibodies at 4 months, alopecia at 7 months, vitiligo, uveitis due to Vogt-Koyanagi-Harada disease at 8 months after clinical resolution of the DiHS/DRESS. 30368475 2018
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE We identified all studies that assessed the changes of TPO-Ab and Tg-Ab in patients with AIT under the treatment of vitamin D from PubMed, Embase, The Cochrane Library, Chinese National Knowledge Infrastructure, Wanfang, and VIP Database. 29388046 2018
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE In our study, prevalence of TPO-Ab positivity is more frequent in subjects with <i>H. pylori</i> infection.Our findings suggest <i>H. pylori</i> infection may play a role in the development of autoimmune thyroiditis. 28092700 2017
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE Instead, our finding that low dietary Se potentiates the development of autoantibodies to Tg and TPO in females is consistent with reports in humans of an increased prevalence of autoimmune thyroiditis in low-Se regions. 28938453 2017
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE The percentage positive for thyroid peroxidase (TPO) antibody and lymphocytic thyroiditis was significantly higher in the TgAb-positive group. 28493284 2017
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 AlteredExpression disease BEFREE Results showed that DHA can visibly reduce antithyroglobulin antibody and thyroid peroxidase antibody levels and regulate T helper cells (Th) 1/Th2 imbalance of experimental AIT mice. 29383139 2017
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 AlteredExpression disease BEFREE Autoimmune thyroiditis with raised levels of thyroperoxidase antibodies (TPO-Abs) is related to bipolar disorder and may be such an endophenotype. 17141745 2007
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE The presence of anti-TPO antibodies strongly suggests autoimmune thyroiditis. 17010173 2006
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE It has been reported that serum of patients with RTH lacks autoantibodies against thyroglobulin (Tg) and thyroid peroxidase (TPO), except in rare cases where there is co-occurrence of coincidental autoimmune thyroiditis. 16723809 2006
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE Modulation of T cell function by alpha-fetoprotein: An in vivo study on porcine thyroid peroxidase-induced experimental autoimmune thyroiditis in transgenic mice producing human alpha-fetoprotein. 10213924 1999
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis
0.100 Biomarker disease BEFREE The enzyme thyroid peroxidase (TPO) plays a central role in thyroid hormone synthesis and is the target for the autoimmune attack in lymphocytic thyroiditis. 2742742 1989