C3, complement C3, 718

N. diseases: 343; N. variants: 49
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE Complement C3a receptor (C3aR) is a key mediator of post-ischemic cerebral injury, and pharmacological antagonism of the C3a receptor is neuroprotective in stroke. 31138990 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE To determine the role of C3a-C3a receptor signalling in ischaemia-induced neural plasticity, we subjected C3a receptor-deficient mice, GFAP-C3a transgenic mice expressing biologically active C3a in the central nervous system, and their respective wild-type controls to photothrombotic stroke. 27956400 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE Complement C3 and C-reactive protein are elevated in South Asians independent of a family history of stroke. 16809564 2006
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group LHGDN Alterations in plasma complement levels after human ischemic stroke. 16823297 2006