Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma
0.040 Biomarker disease BEFREE TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma. 30850732 2019
CUI: C0025202
Disease: melanoma
melanoma
0.040 AlteredExpression disease BEFREE MAP3K7 (known as TAK1), a serine/threonine kinase along the MAPK signaling pathway, was over-expressed in melanoma but decreased following ectopic expression of miR-377. 25889255 2015
CUI: C0025202
Disease: melanoma
melanoma
0.040 Biomarker disease BEFREE These data extend current understanding of cell death-associated functions, underscore the strong therapeutic promise of H11/HspB8 and identify TAK1 as a potential intervention target in melanoma. 22898869 2012
CUI: C0025202
Disease: melanoma
melanoma
0.040 Biomarker disease BEFREE The data indicate that H11/HspB8 overload causes melanoma growth arrest and apoptosis through TAK1 activation and suggest that H11/HspB8 is a promising molecular therapy target. 17173073 2007