TRAF2, TNF receptor associated factor 2, 7186

N. diseases: 111; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE Overall, our results indicate the importance of the S100A8/A9-NPTNβ axis in lung cancer disseminative progression and reveal a pivotal role of its newly identified downstream signaling, TRAF2/RAS-NFIA/NFIB-SPDEF, in linking to the aggressive development of lung cancers. 30720226 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE MAPK1, SRC, SMAD4, EEF1A1, TRAF2 and PLCG1 might be responsible for the development of smoking-induced lung cancer. 26518718 2016
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 AlteredExpression disease BEFREE Further support for the role of TRAF2 in cancer comes from the observations that TRAF2 is overexpressed in both lung adenocarcinoma tissues and multiple lung cancer cell lines. 18794145 2008