Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.020 Biomarker group BEFREE The main findings of our study were: (a) TRPM2-KO had a protective effect on epilepsy; (b) TRPM2-KO improved spatial memory deficits overtime during epilepsy, but it did not improve anxiety; (c) the protective effect probably occurred via the PARP1 downstream signaling pathway; (d) TRPM2-KO could ameliorate epilepsy-induced hippocampal pathological damages and weaken astrocyte activation. 31794795 2020
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.020 Biomarker group BEFREE Trpm2-deficient mice exhibited BD-related behavior such as increased anxiety and decreased social responses, along with disrupted EEG functional connectivity. 26311765 2015