Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain
0.050 Biomarker phenotype BEFREE TRPM2 contributes to neuronal injury in the brain caused by stroke and cardiac arrest among other diseases including cancer, inflammation, and pain. 31772034 2020
CUI: C0030193
Disease: Pain
Pain
0.050 Biomarker phenotype BEFREE Notable progress in delineating the role of TRPM2 in pain has been achieved during the past decade. 29327205 2018
CUI: C0030193
Disease: Pain
Pain
0.050 Biomarker phenotype BEFREE TRPM2 is thought to play important roles in the immune system, in pain and in insulin secretion, but the mechanisms are unclear. 29552700 2018
CUI: C0030193
Disease: Pain
Pain
0.050 Biomarker phenotype BEFREE In order to better characterize the actions of MEL and Se in diabetes-induced peripheral pain and hippocampal injury through modulation of TRPM2 and TRPV1, we tested the effects of MEL and Se on apoptosis and oxidative stress in the hippocampal and dorsal root ganglion (DRG) neurons of streptozotocin (STZ)-induced diabetic rats. 26957303 2017
CUI: C0030193
Disease: Pain
Pain
0.050 Biomarker phenotype BEFREE Therefore, we investigated the contribution of TRPM2 and TRPV1 to pain, oxidative stress, and apoptosis in a rat model of FM and the therapeutic potential of Se. 29235496 2017