TSC2, TSC complex subunit 2, 7249

N. diseases: 410; N. variants: 317
Disease: Renal carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.050 Biomarker disease BEFREE Heterozygous Tsc2 (Tsc2+/-) mouse model to study induced renal cancer in response to ionizing radiation at low doses. 30508035 2019
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.050 Biomarker disease BEFREE Kidney cancer tissue from patients with diabetes showed a higher activity of Akt and decreased in total protein of tuberin compared to kidney cancer patient without diabetes or diabetes alone. 24797175 2014
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.050 GeneticVariation disease BEFREE Functional inactivation of tuberous sclerosis 2 gene (Tsc2) leads to renal carcinogenesis in the hereditary renal carcinoma Eker rat models. 14990989 2004
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.050 GeneticVariation disease BEFREE The Eker (Tsc2 gene mutant) rat model of hereditary renal carcinoma (RC) is an example of Mendelian dominantly inherited predisposition to a specific cancer in an experimental animal. 14566856 2003
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.050 GeneticVariation disease BEFREE Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. 7972075 1994