TTF1, transcription termination factor 1, 7270

N. diseases: 134; N. variants: 2
Disease: Merkel cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007129
Disease: Merkel cell carcinoma
Merkel cell carcinoma 		0.020 Biomarker disease BEFREE In conclusion, there are increasing reports of TTF1+ CK20- skin lesions without signs of systemic disease which behave clinically and prognostically like a PCNC. 31148874 2020
CUI: C0007129
Disease: Merkel cell carcinoma
Merkel cell carcinoma 		0.020 Biomarker disease BEFREE Combined MCC differed from conventional MCC in earlier AJCC stage, increased risk of recurrence and death, decreased CD8 infiltrates, more frequent TTF1 positivity (5/8), abnormal p53 expression (8/8), and frequent lack of large T antigen expression (7/8). 29594354 2018