C5AR1, complement C5a receptor 1, 728

N. diseases: 179; N. variants: 2
Disease: Meningococcemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025306
Disease: Meningococcemia
Meningococcemia 		0.020 Biomarker disease BEFREE Thus, C5aR1 and C5aR2 augment disease pathology and are interesting targets for treatment, whereas C3aR is protective in experimental meningococcal sepsis. 31274379 2019
CUI: C0025306
Disease: Meningococcemia
Meningococcemia 		0.020 Biomarker disease BEFREE Here, we dissected the specific contribution of C5a receptor 1 (C5aR1), the canonical receptor for C5a, using a mouse model of meningococcal sepsis. 29362231 2018