C5AR1, complement C5a receptor 1, 728

N. diseases: 179; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.020 Biomarker disease BEFREE We first examined the possibility of using siRNA and antisense oligonucleotides (ASOs) for transient knockdown of the human and mouse C5a receptor, an important chemoattractant receptor involved in neutrophil-mediated injury that is associated with myocardial infarction, sepsis, and neurodegenerative diseases. 29990379 2018
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.020 Biomarker disease BEFREE Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model. 20875134 2010