C5AR1, complement C5a receptor 1, 728

N. diseases: 179; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.020 Biomarker disease BEFREE There is evidence that the C5a/C5aR1 axis is critically involved both in physiological bone turnover and in inflammatory conditions affecting bone, including osteoarthritis, periodontitis, and bone fractures. 30247799 2018
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.020 Biomarker disease BEFREE The C5aR may contribute to chondrocyte metabolism and the pathogenesis of arthritis differently between in RA and OA. 12070675 2002