SFTPA2, surfactant protein A2, 729238

N. diseases: 111; N. variants: 11
Disease: Pneumonitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.020 AlteredExpression disease BEFREE LPS-induced CD26/DPP4⁻ rats showed decreased gene expression of SP-A and SP-D and reduced signs of lung inflammation associated with a reduced alveolar influx of macrophages and neutrophils. 30977110 2019
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.020 AlteredExpression disease BEFREE Cu/Zn SOD administered intravenously during HTV ventilation effectively reversed associated pulmonary oxidative stress and lung inflammation (P < 0.05); moreover, it preserved SP-A and SP-D expressions in the lung and increased serum nitric oxide (NO) level, enhancing vascular NO bioavailability. 28747201 2017