TNFRSF4, TNF receptor superfamily member 4, 7293

N. diseases: 123; N. variants: 6
Disease: Encephalomyelitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014070
Disease: Encephalomyelitis
Encephalomyelitis 		0.020 Biomarker disease BEFREE In an experimental autoimmune encephalomyelitis (EAE) disease model, we found that OX40 stimulation inhibited IL-17 and reduced EAE. 27317259 2016
CUI: C0014070
Disease: Encephalomyelitis
Encephalomyelitis 		0.020 Biomarker disease BEFREE The presence of CD134-expressing T cells in brain tissue of MS patients and EAE affected mice, together with the functional evidence provided by the significant decrease in disease score obtained in Cd134(-/-) mice, indicate that interfering with the CD134 molecule in T cells may be an appropriate target for therapeutic intervention in active MS. 14644025 2003