TXN, thioredoxin, 7295

N. diseases: 338; N. variants: 2
Disease: Glaucoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017601
Disease: Glaucoma
Glaucoma 		0.210 Biomarker disease BEFREE Our data suggest that Aβ-mediated retinal neurotoxicity involves impairment of the thioredoxin system and enhanced oxidative stress, potentially implicating this mechanism in the pathogenesis of ARMD and glaucoma. 22564527 2012
CUI: C0017601
Disease: Glaucoma
Glaucoma 		0.210 Biomarker disease RGD The effects of Trx1 and Trx2 overexpression on RGC survival were evaluated 5 weeks after glaucoma induction. 18701913 2009