TXN, thioredoxin, 7295

N. diseases: 338; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE Furthermore, FABP7 overexpression in U87 human glioma cell line revealed higher LD accumulation and higher antioxidant defence enzyme (TRX, TRX reductase 1 [TRXRD1]) expression than mock transfection and protected against apoptosis signalling (p38 MAPK, SAPK/JNK and cleaved caspase 3) activation. 30680690 2019
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE TIGAR knockdown radiosensitizes TrxR1-overexpressing glioma in vitro and in vivo via inhibiting Trx1 nuclear transport. 28338004 2017
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE The alpha 2M induction was also observed in other human glioma cell lines (T70 and ADF) and in human fetal astrocyte cultures following IFN gamma treatment. 7519632 1994