TYR, tyrosinase, 7299

N. diseases: 281; N. variants: 121
Disease: Skin Pigmentation Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1704421
Disease: Skin Pigmentation Disorder
Skin Pigmentation Disorder 		0.030 Biomarker group BEFREE Tyrosinase (Tyr) catalyzes the rate-limiting step of melanogenesis in human skin and is thus the main target for treating pigmentation disorders today. 30629444 2019
CUI: C1704421
Disease: Skin Pigmentation Disorder
Skin Pigmentation Disorder 		0.030 Biomarker group BEFREE Pigmentation disorders are attributed to excessive melanin which can be produced by tyrosinase. 30366788 2018
CUI: C1704421
Disease: Skin Pigmentation Disorder
Skin Pigmentation Disorder 		0.030 Biomarker group BEFREE These findings may be helpful to understand the inhibition mechanism of quercetin on tyrosinase and functional research of quercetin in the treatment of pigmentation disorders. 28873682 2017