UCHL1, ubiquitin C-terminal hydrolase L1, 7345

N. diseases: 260; N. variants: 7
Disease: Childhood Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 Biomarker disease BEFREE Here, we show that UCH-L1 reflects GC lineage in lymphoma and is an oncogenic biomarker of aggressive GCB-DLBCL. 26702068 2016
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 AlteredExpression disease BEFREE PU.1-dependent regulation of UCH L1 expression in B-lymphoma cells. 21504384 2011
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 Biomarker disease BEFREE The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling. 20574456 2010