SCGB1A1, secretoglobin family 1A member 1, 7356

N. diseases: 133; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035455
Disease: Rhinitis
Rhinitis
0.050 AlteredExpression disease BEFREE Serum CC16 levels in the children with rhinitis who develop asthma and carry the AA genotype were significantly lower than those who carry the non-AA genotype and those who did not develop asthma. 21255142 2011
CUI: C0035455
Disease: Rhinitis
Rhinitis
0.050 GeneticVariation disease BEFREE The SCGB1A1 38A allele was associated with lower rhinitis prevalence in Greenland but not in Denmark. 19796192 2010
CUI: C0035455
Disease: Rhinitis
Rhinitis
0.050 GeneticVariation disease BEFREE For CC16 A38G, an interaction was significant for ever rhinitis (P(interaction) = 0.006), rhinitis <12 mo (P(interaction) = 0.004), and marginally significant for ever hayfever (P(interaction) = 0.07), allergic eye symptoms <12 mo (P(interaction) = 0.09); their risk allele was G in Russians and A in Finns. 19222419 2009
CUI: C0035455
Disease: Rhinitis
Rhinitis
0.050 AlteredExpression disease BEFREE There was an inverse relation between nasal fluid CC16 levels and symptoms and signs of rhinitis in allergen-challenged patients with IAR. 17298427 2007
CUI: C0035455
Disease: Rhinitis
Rhinitis
0.050 Biomarker disease LHGDN Low levels of CC16 in nasal fluid of children with birch pollen-induced rhinitis. 15813809 2005