UGDH, UDP-glucose 6-dehydrogenase, 7358

N. diseases: 35; N. variants: 2
Disease: Icterus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022346
Disease: Icterus
Icterus 		0.010 Biomarker phenotype BEFREE Our results show that the C2 and C8 positions of 6TP are pivotal in said inhibition towards UDPGDH and have no effect upon UGT1A1, and that blocking C8 could lead to new analogs with reduced, if not eliminated jaundice and liver toxicities. 29324279 2018