Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1328504
Disease: Hormone refractory prostate cancer
Hormone refractory prostate cancer
0.040 AlteredExpression disease BEFREE We propose a novel mechanism by which ADRB2 may affect the development of CRPC through downregulation of UGT2B15 and UGT2B17. 26646591 2016
CUI: C1328504
Disease: Hormone refractory prostate cancer
Hormone refractory prostate cancer
0.040 Biomarker disease BEFREE Furthermore, this study also identifies the UGT2B15 gene as a negatively regulated target gene in castration-resistant prostate cancer and lymph node metastases. 22170718 2012
CUI: C1328504
Disease: Hormone refractory prostate cancer
Hormone refractory prostate cancer
0.040 AlteredExpression disease BEFREE The androgen receptor (AR) and enzymes (AKR1C3, HSD17B2, HSD17B3, UGT2B15 and UGT2B17 ) that are involved in the metabolism of adrenal steroids were upregulated in castration resistant prostate cancer (CRPC). 21365123 2011
CUI: C1328504
Disease: Hormone refractory prostate cancer
Hormone refractory prostate cancer
0.040 AlteredExpression disease BEFREE The alteration of UGT2B15 expression in LNCaP-SF cells is proposed as a biological characteristic involved in the growth of hormone-refractory prostate cancer. 12646996 2003