UMPS, uridine monophosphate synthetase, 7372

N. diseases: 102; N. variants: 8
Disease: Hyperbilirubinemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020433
Disease: Hyperbilirubinemia
Hyperbilirubinemia 		0.010 GeneticVariation disease BEFREE The multivariate logistic regression revealed that OPRT 638G>C polymorphism was associated with grade 3 diarrhea [odds ratio (OR) 19.84 for patients with the C/C homozygous type compared with patients with wild type, P = 0.014] and polymorphisms of UGT1A1 were associated with hyperbilirubinemia (OR 38.76 for homozygotes and double heterozygotes of *6 or *28 compared with wild type, P = 0.0008). 20647221 2011