UMPS, uridine monophosphate synthetase, 7372

N. diseases: 102; N. variants: 8
Disease: Malaria ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024530
Disease: Malaria
Malaria 		0.020 GeneticVariation disease BEFREE Based on the proteomic data and structural modeling, it is surmised that the human malaria parasite low complexity region is responsible for the OPRT-OMPDC interaction. 24507637 2014
CUI: C0024530
Disease: Malaria
Malaria 		0.020 Biomarker disease BEFREE We have previously shown that orotate phosphoribosyltransferase (OPRT) and orotidine 5'-monophosphate decarboxylase (OMPDC) in human malaria parasite Plasmodium falciparum form an enzyme complex, containing two subunits each of OPRT and OMPDC. 19800871 2009