VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation disease BEFREE We sought to examine the relevance of VEGF gene polymorphisms to asthma in the Chinese Han population. 27173321 2016
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation disease BEFREE The ADAM33 rs528557/S2 and the VEGFA rs833069 SNPs were associated with Thai asthmatics, as well as with other populations worldwide. 31586488 2019
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation disease BEFREE The objective of the present study was to determine whether VEGF single nucleotide polymorphisms (SNPs) are associated with asthma, lung function and airway responsiveness. 19196819 2009
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation disease BEFREE We sought to evaluate the effects of variations in the gene coding VEGF receptor (VEGFR) 2 on intermediate phenotypes of asthma in the Korean population. 16630933 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation disease BEFREE We studied VEGFA gene variants and plasma levels and the development of lung function, bronchial hyperresponsiveness and asthma in childhood. 24152156 2013
CUI: C0004096
Disease: Asthma
Asthma
0.400 GeneticVariation disease BEFREE The -2549 -2567 del18 Polymorphism in VEGF and Irreversible Bronchoconstriction in Asthmatics. 30574871 2019
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthmatics. 31831011 2019
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE C. pneumoniae infection of BECs may play a role in the pathogenesis of asthma through the enhanced production of CCL20 and VEGF. 19479364 2009
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease CTD_human Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. 15201500 2004
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease CTD_human Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation. 19263519 2009
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN The aim of this study was to compare vascular endothelial growth factor (VEGF) and its receptor foetal liver kinase (Flk)-1 expression between seasonal AR patients with or without asthma and non-allergic controls as well as that between AR patients with and without asthma. 17651148 2007
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in airway remodeling. 17168735 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma. 23391391 2013
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses. 16461129 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE The cytokine and potent angiogenic factor vascular endothelial growth factor (VEGF) plays an important role in airway remodelling in various airway diseases such as idiopathic pulmonary fibrosis, pulmonary hypertension, lung cancer, asthma and chronic obstructive pulmonary disease (COPD). 17906365 2007
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Role of licochalcone A in VEGF-induced proliferation of human airway smooth muscle cells: implications for asthma. 28635361 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Experimental models and expression studies suggest that anti-vascular endothelial growth factor (VEGF) receptor strategies may be of use in patients with emphysema, whereas anti-HER1-directed strategies may be more useful in patients with pulmonary mucus hypersecretion, as seen in chronic bronchitis and asthma. 17406066 2007
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthma. 28056993 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE VEGFA was a hub protein in both the PPI networks of DEGs in notSA vs. NC and SA vs. NC. 27842724 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Nasal VEGF was also measured in a cohort of asthmatics with verified rhinovirus and respiratory syncytial virus (RSV) infection. 16555282 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE We conclude that ASM-derived VEGF, through modulation of the extracellular matrix, may play an important role in airway remodeling seen in asthma. 14633511 2004
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Increased VEGF serum concentration is characteristic of patients with asthma, especially those with irreversible bronchoconstriction. 30740942 2019
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Insights into the importance of vascular endothelial growth factor and angiogenesis in asthma pathogenesis now lead to potential new therapeutic possibilities and elucidate why recent advances in asthma therapeutics have been so successful. 18188016 2008
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent. 14633511 2004
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthmatics. 27579513 2016