|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Identification and localization of alternately spliced mRNAs for vascular endothelial growth factor in human uterus and estrogen regulation in endometrial carcinoma cell lines.
|
8481475 |
1993 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In addition, ten examples of endometrial carcinoma were evaluated for VPE/VEGF protein expression by immunohistochemistry.
|
8697391 |
1996 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Messenger RNA encoding VEGF was detected in all tissues studied and was more densely expressed in endometrial carcinoma.
|
9032563 |
1996 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Vascular endothelial growth factor expression is not regulated by estradiol or medroxyprogesterone acetate in endometrial carcinoma.
|
8626126 |
1996 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Expressions of vascular endothelial growth factor (VEGF) and its mRNA in uterine endometrial cancers.
|
10381125 |
1998 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The induction of VEGF by progestins is also cell type specific and does not occur in human breast cancer cell lines MCF-7, ZR-75, or MDA-MB-231, nor in Ishikawa cells derived from a human endometrial carcinoma.
|
9458078 |
1998 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
VEGF and TP may cooperatively promote angiogenesis in endometrial cancer, but these expressions may have limited additional prognostic value.
|
10468067 |
1999 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins.
|
10816575 |
2000 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Therefore, insulin could contribute to the increased risk of endometrial carcinoma due to its ability to induce VEGF expression and thus participate in the maintenance of an angiogenic phenotype.
|
11232025 |
2001 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
COX-2 is upregulated in endometrial cancer and facilitates tumor growth via angiogenesis produced in associated with VEGF and TP.
|
11957147 |
2002 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this study, we aimed to study VEGF expression in endometrial carcinoma cells and the effect of p53 gene transfection on VEGF expression using p53-mutated endometrial carcinoma cell line, HEC-50B.
|
12971625 |
2003 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF expression was downregulated by p53 in endometrial carcinoma cells.
|
12782015 |
2003 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Expression of the VEGF and angiopoietin genes in endometrial atypical hyperplasia and endometrial cancer.
|
12942123 |
2003 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
A strong expression of VEGF-A mRNA was significantly seen in carcinosarcomas compared to high-grade endometrial carcinomas.
|
15581949 |
2004 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Sex steroid-dependent VEGF and TP are highly expressed in cases of early stage and well-differentiated uterine endometrial cancers, and basic fibroblast growth factor (bFGF) in cases of advanced and poorly differentiated uterine endometrial cancers.
|
15860258 |
2005 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Further work is needed to establish if IGF-1 plays a role in a subset of endometrial cancers and if isoforms of VEGF play a role in endometrial cancer.
|
15917160 |
2005 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Estrogen receptors alpha and beta regulate production of VEGF in both breast and endometrial cancer cells.
|
16267616 |
2006 |
|
Endometrial Carcinoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The present study is the first case-control study of VEGF and ANGPT-2 polymorphisms in relation to ovarian, cervical, and endometrial cancers.
|
17630849 |
2007 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
The aim of this study is to investigate the angiogenetic process by determining the levels of vascular endothelial growth factor (VEGF), monocyte chemoattractant protein (MCP)-1 and interleukin (IL)-8 in endometrial cancer cells and to study the effect of nimesulide, a selective COX-2 inhibitor, on these mediators using cell culture.
|
17380299 |
2007 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Regulation of the vascular endothelial growth factor and growth by estrogen and antiestrogens through Efp in Ishikawa endometrial carcinoma cells.
|
19148513 |
2009 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To test the hypothesis that restoring HIF-1alpha in cultured cells would restore the ability of E(2) to induce VEGF expression, we treated human endometrial cancer cells (ECC-1) with cobalt chloride (CoCl(2);100 microm), which prevents oxygen-induced HIF-1alpha degradation.
|
19819950 |
2009 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Expression of VEGF mRNA in the groups of EC and atypical hyperplasia (AH) was significantly increased in comparison with the groups of NE (P<0.05).
|
20127022 |
2010 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Biologically inhibitory effects of VEGF siRNA on endometrial carcinoma cells.
|
22057922 |
2011 |
|
Endometrial Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The mutant stroma cells also had higher levels of vascular endothelial growth factor and stromal derived factor signaling components and diminished expression of estrogen receptor α and progesterone receptor, which is common in advanced stages of human endometrial cancer and is an indicator of poor prognosis.
|
21363919 |
2011 |
|
Endometrial Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades.
|
22178239 |
2012 |