|
CATARACT 30
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells.
|
24142690 |
2013 |
|
CATARACT 30
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
CATARACT 30
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Sporadic and Familial Congenital Cataracts: Mutational Spectrum and New Diagnoses Using Next-Generation Sequencing.
|
26694549 |
2016 |
|
CATARACT 30
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Targeted Exome Sequencing of Congenital Cataracts Related Genes: Broadening the Mutation Spectrum and Genotype-Phenotype Correlations in 27 Chinese Han Families.
|
28450710 |
2017 |
|
CATARACT 30
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
|
|
|
|
CATARACT 30
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Dominant cataract formation in association with a vimentin assembly disrupting mutation.
|
19126778 |
2009 |
|
CATARACT 30
|
0.800 |
Biomarker
|
disease |
MGD |
|
|
|
|
Cataract, Pulverulent
|
0.600 |
GermlineCausalMutation
|
disease |
ORPHANET |
Here, we demonstrate that a mutation in VIM causes a dominant, pulverulent cataract.
|
19126778 |
2009 |
|
Cataract, Pulverulent
|
0.600 |
Biomarker
|
disease |
MGD |
|
|
|
|
Cataract, Pulverulent
|
0.600 |
Biomarker
|
disease |
HPO |
|
|
|
|
Nephrosis
|
0.500 |
Biomarker
|
disease |
RGD |
To gain insight into the role of IF proteins in podocytes, we investigated the expression of nestin, vimentin, and desmin in puromycin aminonucleoside (PAN) nephrosis.
|
16418842 |
2006 |
|
Nephrosis
|
0.500 |
Biomarker
|
disease |
CTD_human |
To gain insight into the role of IF proteins in podocytes, we investigated the expression of nestin, vimentin, and desmin in puromycin aminonucleoside (PAN) nephrosis.
|
16418842 |
2006 |
|
CATARACT, COPPOCK-LIKE
|
0.500 |
Biomarker
|
disease |
MGD |
|
|
|
|
CATARACT, COPPOCK-LIKE
|
0.500 |
GermlineCausalMutation
|
disease |
ORPHANET |
Dominant cataract formation in association with a vimentin assembly disrupting mutation.
|
19126778 |
2009 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Using null and knock-down cells and overexpression models, we also show that regulation of breast cancer cell migration in two- and three-dimensional matrices by vimentin is Axl- dependent and that Axl functionally contributes to lung extravasation of breast cancer cells in mice.
|
21057535 |
2011 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
COPB2 is up-regulated in breast cancer and plays a vital role in the metastasis via N-cadherin and Vimentin.
|
31119859 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The levels of miR-7 expression was positively correlated with E-CADHERIN mRNA and negatively correlated with VIMENTIN mRNA levels in breast cancer samples.
|
22876288 |
2012 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In summary, distinct sites within the vimentin gene appear to be important for the control of vimentin expression in V+ and V- breast cancer cells with multiple elements acting coordinately to regulate vimentin expression.
|
7986748 |
1994 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
They represent both luminal and basal breast cancer subtypes based on the relative gene expression of cytokeratin (CK) 8/CK18 and CK5/CK17, respectively, and those that have undergone an epithelial-to-mesenchymal transition (post-EMT) based on their expression of vimentin and the loss of CKs.
|
17268817 |
2007 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Imaging of breast cancer cell lines revealed that WFA induces perinuclear vimentin accumulation followed by rapid vimentin depolymerization.
|
21538350 |
2011 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
HIPK2 downregulates vimentin and inhibits breast cancer cell invasion.
|
22236966 |
2012 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
CTD_human |
Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K.
|
25330770 |
2014 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our present results demonstrate that, despite analogies between vimentin-positive breast cancers and myoepithelial cells in their expression of differentiation-related proteins, neither myoepithelial histogenesis nor EMT can exclusively explain the biology of these distinct tumours.
|
15906273 |
2005 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Quantification of the examined molecules revealed that the median intensity of TUB, GLU, and VIM was significantly increased in patients with metastatic BC compared with those with early disease (TUB, 62.27 vs 11.5, p = 0.0001; GLU, 6.99 vs 5.29, p = 0.029; and VIM, 8.24 vs 5.38, p = 0.0001, respectively).
|
29976237 |
2018 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Data on 21 MCC and 19 MBC patients are analyzed, and it revealed that the CTC numbers decreased with aspirin treatment in MCC (p < 0.001) but not MBC (p = 0.0532); besides, ratio of E+ CTCs increased (p = 0.037) and M+ CTCs decreased at 2 months in MCC (p = 0.013), but neither the ratio of E+ or M+ CTCs changes significantly in MBC; vimentin expression of M+ CTCs is higher than E+ and B+ CTCs either in MBC or MCC patients at baseline (p < 0.01); and aspirin suppresses the vimentin expression in M+ (p = 0.002)and B+ (p = 0.006) CTCs of MCC and M+ CTCs of MBC (p = 0.004); besides it find vimentin expression in B+ (p = 0.004) or M+ (p < 0.001), CTCs are markedly decreased in patients with total CTC numbers declined.
|
29243075 |
2018 |