VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002447
Disease: Amelia
Amelia
0.010 Biomarker disease BEFREE The results are compared with the existing software packages mice, VIM and Amelia in simulation studies. 29451087 2019
CUI: C0003486
Disease: Aortic Aneurysm
Aortic Aneurysm
0.010 Biomarker disease BEFREE This was accompanied by the appearance of fibrosis biomarkers including vimentin, collagen-I, and hydroxyproline, in the liver of TAA-treated OVX rats. 31362375 2019
CUI: C0018378
Disease: Guillain-Barre Syndrome
Guillain-Barre Syndrome
0.010 Biomarker disease BEFREE Vimentin null mice were protected from WT GBS infection and also exhibited less inflammatory cytokine production in brain tissue. 31181121 2019
CUI: C0019158
Disease: Hepatitis
Hepatitis
0.010 AlteredExpression group BEFREE In HBs-Tg mice, poly (I:C) induced liver inflammation with markedly increased infiltrating lymphocytes, along with the concurrently increased apoptosis and proliferation of hepatocytes, leading to the accelerated epithelial-to-mesenchymal transition (EMT) of hepatocytes shown by increased expression of the typical transcriptional factors (Slug, Twist, and mothers against decapentaplegic-interacting protein 1) and phenotypic proteins (vimentin and chemokine [C-X-C motif] receptor 4). 30329167 2019
CUI: C0022548
Disease: Keloid
Keloid
0.010 Biomarker disease BEFREE Identified by the IF staining of Vimentin, a classical biomarker of fibroblast, both primary culture of keloid and normal skin fibroblasts have been established. 31696499 2019
CUI: C0023794
Disease: Lipoidosis
Lipoidosis
0.010 Biomarker disease BEFREE The amounts of the following proteins were increased in stable atherosclerotic plaques at the stage of lipidosis and fibrosis: vimentin, tropomyosin β-chain, actin, keratin, tubulin β-chain, microfibril-associated glycoprotein 4, serum amyloid P-component, and annexin 5. 31703357 2019
CUI: C0026837
Disease: Muscle Rigidity
Muscle Rigidity
0.010 Biomarker phenotype BEFREE Our experimental results show that elevation of rigidity and invasiveness of TGFβ-stimulated NSCLC cells correlates with upregulation of several cytoskeletal and motor proteins including vimentin, a canonical marker of EMT, and less-known unconventional myosins. 31113982 2019
CUI: C0026936
Disease: Mycoplasma Infections
Mycoplasma Infections
0.010 Biomarker group BEFREE In HCC patients, most of p37-negative CTCs (95%) showed intermediate phenotype with neither EpCAM nor vimentin expression, but p37-positive CTCs were EpCAM-positive (44%), vimentin-positive (32%), and both negative (24%), suggesting that EpCAM-positive CTCs are enriched with mycoplasma infection. 30980864 2019
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.010 Biomarker disease BEFREE Three injury models (apical resection, ischemia/reperfusion, and myocardial infarction) were used to identify the location and cell type of ciliated cells with the use of antibodies specific for cilia (acetylated tubulin, γ-tubulin, polycystin [PC] 1, PC2, and KIF3A), fibroblasts (vimentin, α-smooth muscle actin, and fibroblast-specific protein-1), and cardiomyocytes (α-actinin and troponin I). 30818997 2019
CUI: C0027149
Disease: Myxoma
Myxoma
0.010 Biomarker disease BEFREE Based on ROC (receiver operating characteristics) statistical analysis, c-MYC, HIF-1α, p53, and vimentin may be considered potential biomarkers for malignancy detection in myxoma. 30900156 2019
CUI: C0027441
Disease: Nasopharyngitis
Nasopharyngitis
0.010 AlteredExpression disease BEFREE The clinical immunohistochemistry detection showed the positive expression ratio of vimentin was 24.6% (14/57) of the NPC specimens, whereas vimentin expression was negative in nasopharyngitis (NPG) tissues (0/20, P = 0.016). 30833029 2019
CUI: C0029172
Disease: Oral Submucous Fibrosis
Oral Submucous Fibrosis
0.010 AlteredExpression disease BEFREE BMP4 is overexpressed in OSF and plays a role in EMT, as its expression correlates with the expression of E-cadherin and vimentin. 31397922 2019
CUI: C0036117
Disease: Salmonella infections
Salmonella infections
0.010 Biomarker group BEFREE Particularly the occurrence of VIM-1-producing <i>Salmonella</i> Infantis in livestock farms is worrisome, as this zoonotic pathogen is one of the main causes for human salmonellosis in Europe. 31189558 2019
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.010 AlteredExpression disease BEFREE <b>Results:</b> VICM and BGM levels were increased in early compared with late dSSc (<i>p</i>< =0.023). 30457356 2019
CUI: C0041182
Disease: Trophoblastic Neoplasms
Trophoblastic Neoplasms
0.010 Biomarker group BEFREE We studied the immunoexpression of EMT transcription factors (TWIST1, ZEB1, ZEB2), E-cadherin, and vimentin in 18 trophoblastic tumors and pseudo-tumors. 30847562 2019
CUI: C0042133
Disease: Uterine Fibroids
Uterine Fibroids
0.010 Biomarker group BEFREE Using a tissue microarray technique (TMA), cases of myofibroma (MF), of nodular fasciitis (NF), of desmoplastic fibroma (DF), and of myofibroblastic sarcoma (MS) from the Universidad Autónoma Metropolitana Xochimilco, and a Private Oral Pathology Service in Mexico City were stained with antibodies against alpha-smooth muscle actin (α-SMA), H-caldesmon, vimentin, desmin, β-catenin, CD34, anaplastic lymphoma protein kinase (ALK-1), and Ki-67. 30168888 2019
CUI: C0042345
Disease: Varicosity
Varicosity
0.010 AlteredExpression disease BEFREE In varicose veins and proliferative VSMCs, miR-202 expression was upregulated, with decreased SM-22α expression and increased vimentin and collagen I expression. 30556158 2019
CUI: C0151449
Disease: Primary Sjögren's syndrome
Primary Sjögren's syndrome
0.010 AlteredExpression disease BEFREE In this study, we present data demonstrating a negative correlation of the epithelial marker E-cadherin expression and a positive correlation of mesenchymal vimentin and collagen type I expression with increasing degrees of tissue inflammation in pSS SG specimens. 31165469 2019
CUI: C0151517
Disease: Complete atrioventricular block
Complete atrioventricular block
0.010 AlteredExpression disease BEFREE The methylation frequencies of SOX1 and VIM promoters in HCC patients were significantly higher than those in LC (p<0.001 and p<0.001), CHB (p<0.001 and p<0.001) and HC (p<0.001 and p<0.001) subjects. 28592127 2019
CUI: C0153349
Disease: Malignant neoplasm of tongue
Malignant neoplasm of tongue
0.010 Biomarker disease BEFREE UCA1 knockdown significantly suppressed TGFβ1-induced tongue cancer cell invasion and EMT by decreasing vimentin and increasing E-cadherin. 30635938 2019
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
0.010 AlteredExpression disease BEFREE The maturation of NgR is regulated by the interaction of vimentin and NgR, which attenuates the invasive activity of GBM, and might be a potential therapeutic target for brain cancer. 31649250 2019
CUI: C0206623
Disease: Adenosquamous carcinoma
Adenosquamous carcinoma
0.010 Biomarker disease BEFREE There were significant immunophenotypic differences between adenosquamous carcinomas and pure invasive stratified mucin-producing carcinomas with regard to HPV (p < 0.0001), PAX8 (p = 0.038; more in adenosquamous carcinoma), p40 (p < 0.0001; more in adenosquamous carcinoma), p63 (p = 0.0018; more in adenosquamous carcinoma) and MUC6 (p  < 0.0001; less in adenosquamous carcinoma), HNF-1beta (p = 0.0023), vimentin (p = 0.0003), p53 (p = 0.0004), and CK7 (p = 0.0002) expression. 30258209 2019
CUI: C0206651
Disease: Clear Cell Sarcoma of Soft Tissue
Clear Cell Sarcoma of Soft Tissue
0.010 Biomarker disease BEFREE A strong expression of S-100, HMB45 and Vimentin was detected in immunohistochemical staining, which was inclined to the diagnosis of the CCS of soft tissue. 31624764 2019
Pituitary-dependent Cushing's disease
0.010 AlteredExpression disease BEFREE Immunohistochemistry revealed higher mean percentage infiltration of CD68+ macrophages and CD4+ T lymphocytes, increased mean area of CD11c+ M1 macrophages, higher number of CD11c+ crownlike structures, and decreased vimentin in the AT of patients with active CD compared with controls. 30722035 2019
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
0.010 Biomarker disease BEFREE Immunohistochemical staining demonstrated cells labeled with VIM (+), CD68PGM1 (+), CD34 (-), Actin (-), PCK (-), EMA (-), Desmin (-), SMA (-), S-100 (-), P63 (-), ALK-1 (-), beta-catenia (+), and KI67 (+). 31169683 2019