Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE Therefore, simultaneous inhibition of VPAC1 and EGFR, in turn, might inhibit the progression of breast carcinoma. 30810849 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE Results give value to the specific signaling of VIP through VPAC(1) receptor in human breast cancer cells and support the potential use of VPAC(1)-receptor antagonists in combined targeted therapies for breast cancer. 21896307 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE The two hypervariable regions HVR1 and HVR2 in the D-Loop region were sequenced in ten paired tissue and plasma samples from breast cancer patients. 22199290 2011
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE The transgenic MMTVneu mice spontaneously develop BC and metastatic lesions that overexpress cyclin D1 and VPAC1 biomarkers. 20008985 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE Previous studies have shown that vasoactive intestinal peptide (VIP) and its receptors (VPAC(1) and VPAC(2) receptors) are involved in promotion and growth of many human tumours including breast cancer. 17683807 2007
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE Breast cancer VPAC1 receptors. 16888206 2006
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE These results indicate that VIP-E derivatives function as breast cancer VPAC(1) receptor agonists which inhibit MCF-7 cellular viability. 12088760 2002
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 Biomarker disease BEFREE Three breast carcinoma cell lines were tested for 17beta-estradiol (E(2)) mediated regulation of vasoactive intestinal polypeptide receptor type-1 (VPAC(1)) expression. 11165054 2001
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.090 AlteredExpression disease BEFREE Downregulation of VPAC1R expression in breast cancer cell lines. 11193846 2000