|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Schizophrenia
|
0.480 |
Biomarker
|
disease |
BEFREE |
VRK2 has long been known for its relationship with neurodegenerative disorders such as schizophrenia.
|
30062698 |
2018 |
|
Schizophrenia
|
0.480 |
AlteredExpression
|
disease |
BEFREE |
Of 18 antigens tested, 6 (derived from DPYD, MAD1L1, ZNF804A, DRD2, TRANK1, and MMP16, respectively) showed increased IgG levels and 3 (derived from TSNARE1, TCF4, and VRK2, respectively) showed decreased IgG levels in patients with schizophrenia compared with control subjects.
|
29373732 |
2018 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
|
29483656 |
2018 |
|
Schizophrenia
|
0.480 |
PosttranslationalModification
|
disease |
BEFREE |
The results demonstrated significant down-regulation of VRK2 gene in SCZ (P<0.0001), epilepsy (P=0.008) and MS (P=0.029) compared with the healthy subjects.
|
29100046 |
2018 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.
|
27922604 |
2017 |
|
Schizophrenia
|
0.480 |
AlteredExpression
|
disease |
BEFREE |
These results suggest that reduced VRK2 mRNA levels are involved in the underlying mechanisms in schizophrenia spectrum disorders.
|
26941264 |
2016 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
BEFREE |
Our data provides further evidence for the genetic contributions of VRK2 rs2312147 to schizophrenia susceptibility especially in Europeans, while further replication analyses in Asian populations are still needed, and future studies, e.g., the underlying molecular mechanisms of genetic risk, are necessary.
|
27382989 |
2016 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
BEFREE |
Our data provide preliminary evidence that the VRK2 gene might play a major role in the development of SCZ in the Northwest Chinese Han population.
|
26345874 |
2015 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
|
Schizophrenia
|
0.480 |
Biomarker
|
disease |
BEFREE |
Our data provide further evidence for the contribution of VRK2 to schizophrenia.
|
23102693 |
2012 |
|
Schizophrenia
|
0.480 |
Biomarker
|
disease |
PSYGENET |
Our data provide further evidence for the contribution of VRK2 to schizophrenia.
|
23102693 |
2012 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
BEFREE |
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
|
21791550 |
2011 |
|
Schizophrenia
|
0.480 |
Biomarker
|
disease |
PSYGENET |
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
|
21791550 |
2011 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASDB |
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
|
21791550 |
2011 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASDB |
Common variants conferring risk of schizophrenia.
|
19571808 |
2009 |
|
Schizophrenia
|
0.480 |
GeneticVariation
|
disease |
GWASCAT |
Common variants conferring risk of schizophrenia.
|
19571808 |
2009 |