WAS, WASP actin nucleation promoting factor, 7454

N. diseases: 204; N. variants: 37
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.120 Biomarker disease BEFREE The effects of WASp deficiency on B10 cells have been reported by only one group, which used an antigen-induced arthritis model. 25728049 2015
CUI: C0003864
Disease: Arthritis
Arthritis 		0.120 Biomarker disease BEFREE In experimental, antigen-induced arthritis WASp-deficient (WASp knockout [WAS KO]) mice developed exacerbated disease associated with decreased Breg cells and regulatory T (Treg) cells, but increased Th17 cells in knee-draining LNs. 24945741 2014
CUI: C0003864
Disease: Arthritis
Arthritis 		0.120 Biomarker disease HPO