WT1, WT1 transcription factor, 7490

N. diseases: 446; N. variants: 61
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 AlteredExpression group LHGDN Wilms' tumor 1 suppressor gene mediates antiestrogen resistance via down-regulation of estrogen receptor-alpha expression in breast cancer cells. 18708366 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 AlteredExpression group LHGDN The Wilms' tumor suppressor WT1 inhibits malignant progression of neoplastigenic mammary epithelial cells. 18751389 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 Biomarker group LHGDN Wilms' tumor protein 1: an early target of progestin regulation in T-47D breast cancer cells that modulates proliferation and differentiation. 17599043 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 Biomarker group LHGDN Growth inhibition of breast cancer cell line MCF-7 by siRNA silencing of Wilms tumor 1 gene. 18181329 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 AlteredExpression group BEFREE High levels of the Wilms' Tumor 1 (WT1) protein and mRNA had been associated with aggressive phenotypes of breast tumors. 15674342 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 Biomarker group LHGDN High levels of the Wilms' Tumor 1 (WT1) protein and mRNA had been associated with aggressive phenotypes of breast tumors. 15674342 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 AlteredExpression group LHGDN Inhibition of breast cancer cell growth by the Wilms' tumor suppressor WT1 is associated with a destabilization of beta-catenin. 14666652 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 AlteredExpression group LHGDN Transcriptional activation of c-myc proto-oncogene by WT1 protein. 15286719 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 Biomarker group CTD_human WT1 is a tumor-associated antigen in colon cancer that can be recognized by in vitro stimulated cytotoxic T cells. 14961577 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 Biomarker group LHGDN Downregulation of Wilms' tumor 1 protein inhibits breast cancer proliferation. 12127961 2002
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.390 AlteredExpression group BEFREE The role of these growth factors in breast tumor growth led us to investigate possible WT1 gene expression in normal and cancerous breast tissue. 9223327 1997