Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 GeneticVariation disease BEFREE The combined analysis of XPC Lys939Gln and XPC-PAT variants showed that patients who inherited (Lys/Gln + PAT D/D) genotypes were protected against prostate cancer development compared to controls. 30552616 2019
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 Biomarker disease BEFREE These findings suggested that XPC SNPs may contribute to risk of PCa in Eastern Chinese men. 27974699 2017
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 Biomarker disease BEFREE We assessed the association between genetic variants of XPG, XPA, XPD, CSB, XPC and CCNH in the nucleotide excision repair (NER) pathway and risk of prostate cancer. 24289586 2013
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 GeneticVariation disease BEFREE The aim of our study was to evaluate the impact of XPC gene polymorphisms on PCa risk by using a meta-analysis. 24093803 2013
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 GeneticVariation disease BEFREE Poly (AT) polymorphism in the XPC gene and smoking enhance the risk of prostate cancer in a low-risk Chinese population. 22682619 2012
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 GeneticVariation disease BEFREE XPC exon 15 variant CC genotypes presented statistically significant risk of PCa (Adjusted OR- 2.15, 95% CI-1.09-4.23, P=0.026). 22382185 2012
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 GeneticVariation disease BEFREE This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms in PC, and our present data suggest that XPC Lys939Gln and the T-A haplotype of XRCC1 Arg194Trp and Arg399Gln may be risk factors for PC in Japanese. 17196815 2007