Disease: Malignant neoplasm of colon and/or rectum ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 AlteredExpression disease BEFREE Cox regression analysis showed that high XPC expression might be a potential predictive factor for colorectal cancer. 30109214 2018
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE Lack of associations between XPC polymorphisms and colorectal cancer: a meta-analysis. 26214629 2015
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE Haplotype analysis within XPC, XPD and XPG revealed haplotypes associated with an altered colorectal cancer risk. 25391773 2015
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE This meta-analysis suggested that both the XPC Lys939Gln and Ala499Val polymorphisms were not risk factors for increasing colorectal cancer. 24385304 2014
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE XPC Lys939Gln polymorphism contributes to colorectal cancer susceptibility: evidence from a meta-analysis. 24947936 2014
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE Associations of ABCB1 and XPC genetic polymorphisms with susceptibility to colorectal cancer and therapeutic prognosis in a Chinese population. 23803084 2013
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE (1) The XPC C/A (i11) genotype is associated with an increased risk of sporadic colorectal cancer. 21559836 2012
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE We observed a statistically significant interaction between the XPC Lys939Gln polymorphism and consumption of red meat, with a 3.7-fold increase in colorectal cancer risk per 100g red meat intake per day among carriers of the homozygous variant, but virtually no effect of red meat intake among carriers of the wild type allele. 17363013 2007
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE Our study suggests that genetic polymorphisms in the NER genes, ERCC6 and XPC, may be associated with an increased risk of colorectal cancer. 17119055 2006