ZFP36, ZFP36 ring finger protein, 7538

N. diseases: 161; N. variants: 3
Disease: Iron deficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0240066
Disease: Iron deficiency
Iron deficiency 		0.010 Biomarker disease BEFREE Here, we show that the mRNA-binding protein tristetraprolin (TTP) is induced by iron deficiency and degrades mRNAs of mitochondrial Fe/S-cluster-containing proteins, specifically <i>Ndufs1</i> in complex I and <i>Uqcrfs1</i> in complex III, to match the decrease in Fe/S-cluster availability. 29915044 2018