|
Colorectal Carcinoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
Tonometry
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analyses identify new loci influencing intraocular pressure.
|
29617998 |
2018 |
|
Encephalitis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cortical brain tissues from uninfected (n = 4) and SIV-infected macaques with (SIVE, n = 6) or without encephalitis (SIVnoE, n = 4) were examined using multi-label, semi-quantitative immunofluorescence microscopy of Shh, netrin-1, tight junction protein zona occludens 1 (ZO1), glial fibrillary acidic protein, CD163, platelet-derived growth factor receptor b (PDGFRB), glucose transporter 1, fibrinogen, and SIV Gag p28.
|
30981282 |
2019 |
|
Encephalitis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Infection was confirmed by immunohistochemistry (IHC) using an antibody specific for p28 of VM virus/caprine arthritis and encephalitis virus and by polymerase chain reaction (PCR) in all sheep.
|
29599005 |
2018 |
|
Malignant neoplasm of breast
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
ΔPK induces calpain activation in both melanoma and breast cancer 3D cultures as determined by the loss of the p28 regulatory subunit, and 3D growth is restored by treatment with the calpain inhibitor PD150606.
|
24553345 |
2014 |
|
Breast Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
ΔPK induces calpain activation in both melanoma and breast cancer 3D cultures as determined by the loss of the p28 regulatory subunit, and 3D growth is restored by treatment with the calpain inhibitor PD150606.
|
24553345 |
2014 |
|
Malignant neoplasm of breast
|
0.020 |
Biomarker
|
disease |
BEFREE |
Therefore, our results indicated that the peptide p28 (VLCSIDWFM) could serve as a novel candidate epitope for the development of peptide vaccines against PLAC1-positive breast cancer.
|
21710262 |
2012 |
|
Breast Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Therefore, our results indicated that the peptide p28 (VLCSIDWFM) could serve as a novel candidate epitope for the development of peptide vaccines against PLAC1-positive breast cancer.
|
21710262 |
2012 |
|
Adult T-Cell Lymphoma/Leukemia
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo.
|
18474092 |
2008 |
|
Adult T-Cell Lymphoma/Leukemia
|
0.020 |
Biomarker
|
disease |
BEFREE |
Structural analysis of p28 adult T-cell leukaemia-associated antigen.
|
3014050 |
1986 |
|
Retinopathy of Prematurity
|
0.010 |
Biomarker
|
disease |
BEFREE |
Morphological abnormalities in the retinal vasculature showed a tendency toward spontaneous recovery from P28 to P35 in ROP rats.
|
31788758 |
2020 |
|
Brain Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
After overcoming two phase I trials, a functional region of Azurin called p28 has been approved as a drug for the treatment of brain tumor glioma by FDA.
|
30895406 |
2019 |
|
Glioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
After overcoming two phase I trials, a functional region of Azurin called p28 has been approved as a drug for the treatment of brain tumor glioma by FDA.
|
30895406 |
2019 |
|
Influenza
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, we found that P28 and S65 also affect the shutoff activity of PA-X derived from other influenza virus subtypes.
|
30894843 |
2019 |
|
Caffeine related disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Housing conditions began on postnatal day 24 (P24) and half of the rats were provided caffeine (0.25 g/l) in their drinking water beginning on P28.
|
31045871 |
2019 |
|
Autoimmune Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Interleukin-27 (IL-27) and its subunit P28 (also known as IL-30) have been shown to inhibit autoimmunity and have been suggested as potential immunotherapeutic for autoimmune diseases such as multiple sclerosis (MS).
|
29740452 |
2018 |
|
Multiple Sclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Interleukin-27 (IL-27) and its subunit P28 (also known as IL-30) have been shown to inhibit autoimmunity and have been suggested as potential immunotherapeutic for autoimmune diseases such as multiple sclerosis (MS).
|
29740452 |
2018 |
|
Myocardial Infarction
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We were particularly interested in one novel cardiac-enriched lncRNA, ENSMUST00000117266, whose expression was dramatically down-regulated from P1 to P28 and was also sensitive to hypoxia, paraquat, and myocardial infarction.
|
28266538 |
2017 |
|
Pseudorabies
|
0.010 |
Biomarker
|
disease |
BEFREE |
Transynaptic tracing with pseudorabies virus and double immunofluorescence analysis indicated that VEGF treatment in P28 rats alleviated the reduced number of neurons and improved their network reorganization.
|
29238292 |
2017 |
|
Schizophrenia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study used a rat model to test whether prenatal immune activation with lipopolysaccharide (LPS; at gestation days, GD, 15 and 16) or maternal iron deficiency (from GD2 to postnatal day P7) or the combination of both insults alters major subtypes of GABAergic interneurons (parvalbumin, somatostatin, cholecystokinin) in brain regions relevant to schizophrenia (medial and dorsolateral prefrontal cortex [PFC], hippocampal CA1 and dentate gyrus, ventral subiculum) in offspring at P14 or P28.
|
28214898 |
2016 |
|
Iron deficiency
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study used a rat model to test whether prenatal immune activation with lipopolysaccharide (LPS; at gestation days, GD, 15 and 16) or maternal iron deficiency (from GD2 to postnatal day P7) or the combination of both insults alters major subtypes of GABAergic interneurons (parvalbumin, somatostatin, cholecystokinin) in brain regions relevant to schizophrenia (medial and dorsolateral prefrontal cortex [PFC], hippocampal CA1 and dentate gyrus, ventral subiculum) in offspring at P14 or P28.
|
28214898 |
2016 |
|
Hepatitis C
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In this study we have investigated the potential role of SNPs in the promoter region of IL27 p28 gene (alleles rs153109) on the outcome of HCV infected patients.
|
25236666 |
2014 |
|
melanoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
ΔPK induces calpain activation in both melanoma and breast cancer 3D cultures as determined by the loss of the p28 regulatory subunit, and 3D growth is restored by treatment with the calpain inhibitor PD150606.
|
24553345 |
2014 |
|
Septicemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
We studied the events regulating the p28 subunit of IL-27 in endotoxic shock and polymicrobial sepsis following cecal ligation and puncture.
|
25348624 |
2014 |