LRP8, LDL receptor related protein 8, 7804

N. diseases: 55; N. variants: 10
Disease: Cognition Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders 		0.010 AlteredExpression group BEFREE Our findings demonstrate that age-dependent loss of SFRS11 in the PFC reduces levels of apoE and LRP8, leading to activation of the JNK pathway, ultimately influencing cognitive deficits. 31269452 2019