LRP8, LDL receptor related protein 8, 7804

N. diseases: 55; N. variants: 10
Disease: Atherosclerotic lesion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4703473
Disease: Atherosclerotic lesion
Atherosclerotic lesion 		0.010 Biomarker disease BEFREE The atherosclerotic plaques of Lrp8(-/-)Ldlr(-/-) mice displayed significantly higher levels of p53-positive macrophages, indicating that the apoER2-deficient macrophages contribute to the accelerated atherosclerotic lesion necrosis observed in these animals. 24840660 2014