|
Myocardial Infarction
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
We aim to test the role of the LRP8 gene variants correlating with the lipid profile in MI patients in South Indian population.
|
29032149 |
2018 |
|
Myocardial Infarction
|
0.370 |
Biomarker
|
disease |
BEFREE |
Thus, abnormal apoER2 functions in macrophages may at least in part contribute to the premature coronary artery disease and myocardial infarction in humans with LRP8 polymorphisms.
|
24840660 |
2014 |
|
Myocardial Infarction
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Functional single-nucleotide polymorphism R952Q in LRP8 is associated with familial and early-onset CAD/MI.
|
24867879 |
2014 |
|
Myocardial Infarction
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Like R952Q, LRP8 SNPs rs7546246, rs2297660, rs3737983, and rs5177 were significantly associated with early-onset CAD/MI in both population-based and family-based association studies in GeneQuest.
|
23524007 |
2013 |
|
Myocardial Infarction
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Additive effect of LRP8/APOER2 R952Q variant to APOE epsilon2/epsilon3/epsilon4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study.
|
19439088 |
2009 |
|
Myocardial Infarction
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Recently, an association of the LRP8 rs5174" genes_norm="7804">R952Q polymorphism (rs5174) with familial premature CAD/MI was reported.
|
18592168 |
2008 |
|
Myocardial Infarction
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
This extensive study, involving multiple independent populations, provides the first evidence that genetic variants in LRP8 may contribute to the development of premature and familial CAD and MI.
|
17847002 |
2007 |
|
Myocardial Infarction
|
0.370 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Schizophrenia
|
0.320 |
Biomarker
|
disease |
PSYGENET |
APOER2 gene expression analysis revealed lower transcript levels in lymphoblastoid cells from cognitively impaired schizophrenia patients of the alternatively spliced exon 19, mediating Reelin signaling and synaptic plasticity in the adult brain.
|
22419519 |
2012 |
|
Schizophrenia
|
0.320 |
AlteredExpression
|
disease |
BEFREE |
APOER2 gene expression analysis revealed lower transcript levels in lymphoblastoid cells from cognitively impaired schizophrenia patients of the alternatively spliced exon 19, mediating Reelin signaling and synaptic plasticity in the adult brain.
|
22419519 |
2012 |
|
Schizophrenia
|
0.320 |
Biomarker
|
disease |
PSYGENET |
In this study, we measured the mRNA levels of VLDLR and ApoER2 in blood lymphocytes from patients with schizophrenia (drug-naive patients (n=20) and medicated patients (n=20)) and age-and gender-matched healthy controls (n=40) using quantitative real-time RT-PCR.
|
17936586 |
2008 |
|
Schizophrenia
|
0.320 |
AlteredExpression
|
disease |
BEFREE |
In this study, we measured the mRNA levels of VLDLR and ApoER2 in blood lymphocytes from patients with schizophrenia (drug-naive patients (n=20) and medicated patients (n=20)) and age-and gender-matched healthy controls (n=40) using quantitative real-time RT-PCR.
|
17936586 |
2008 |
|
Alcoholic Intoxication, Chronic
|
0.310 |
Biomarker
|
disease |
PSYGENET |
The gene coding for apolipoprotein E receptor 2 (APOER2) and the gene coding for ubiquitin-associated protein-2 (UBAP2) are among the most appropriate for follow-up in human and nonhuman species as contributors to risk for alcohol dependence.
|
23739027 |
2013 |
|
Alcoholic Intoxication, Chronic
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
The gene coding for apolipoprotein E receptor 2 (APOER2) and the gene coding for ubiquitin-associated protein-2 (UBAP2) are among the most appropriate for follow-up in human and nonhuman species as contributors to risk for alcohol dependence.
|
23739027 |
2013 |
|
Unipolar Depression
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Results from this preliminary study suggest that the expression of ApoER2 may serve as a trait marker for major depressive disorder.
|
20493228 |
2010 |
|
Unipolar Depression
|
0.310 |
AlteredExpression
|
disease |
BEFREE |
Results from this preliminary study suggest that the expression of ApoER2 may serve as a trait marker for major depressive disorder.
|
20493228 |
2010 |
|
Major Depressive Disorder
|
0.310 |
AlteredExpression
|
disease |
BEFREE |
Results from this preliminary study suggest that the expression of ApoER2 may serve as a trait marker for major depressive disorder.
|
20493228 |
2010 |
|
Major Depressive Disorder
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Results from this preliminary study suggest that the expression of ApoER2 may serve as a trait marker for major depressive disorder.
|
20493228 |
2010 |
|
Nerve Degeneration
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2.
|
18172410 |
2008 |
|
Psychotic Disorders
|
0.100 |
GeneticVariation
|
group |
GWASDB |
Common variant at 16p11.2 conferring risk of psychosis.
|
23164818 |
2014 |
|
Low density lipoprotein cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum HDL cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum LDL cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |