EVI5, ecotropic viral integration site 5, 7813

N. diseases: 22; N. variants: 16
Disease: Multiple Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease BEFREE In the current study, we aimed to confirm association of the single nucleotide polymorphisms (SNPs) within EVI5 gene with MS in 410 relapsing-remitting MS patients and 410 controls from Iranian population. 29141798 2017
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease GWASCAT Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis. 26819262 2016
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease BEFREE A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. 26433934 2015
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease GWASCAT Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease BEFREE We then applied this concept to predict and functionally demonstrate that the polymorphic variants associated with multiple sclerosis located within the EVI5 gene impinge on the adjacent gene GFI1. 21602820 2011
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 Biomarker disease BEFREE Our findings agree with the corresponding data of the recent IMSGC study and present new genetic evidence that points to EVI5 as a factor of susceptibility to MS. 20087403 2010
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease BEFREE We also replicated several known MS associations (HLA-DR15, P = 7.0 x 10(-184); CD58, P = 9.6 x 10(-8); EVI5-RPL5, P = 2.5 x 10(-6); IL2RA, P = 7.4 x 10(-6); CLEC16A, P = 1.1 x 10(-4); IL7R, P = 1.3 x 10(-3); TYK2, P = 3.5 x 10(-3)) and observed a statistical interaction between SNPs in EVI5-RPL5 and HLA-DR15 (P = 0.001). 19525955 2009
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation disease BEFREE This study confirms EVI5 as another risk locus for MS; however, much of the genetic basis of MS remains unidentified. 18401352 2008
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 Biomarker disease LHGDN This study confirms EVI5 as another risk locus for MS; however, much of the genetic basis of MS remains unidentified. 18401352 2008