CXCR4, C-X-C motif chemokine receptor 4, 7852

N. diseases: 739; N. variants: 23
Disease: bone destruction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0238790
Disease: bone destruction
bone destruction 		0.010 AlteredExpression disease BEFREE In vivo studies show that overexpression of PTEN dramatically attenuates bone destruction, and this inhibition is associated with reduced CXCR4 expression in tumors. 31571016 2020