Disease: Coronary heart disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 Biomarker disease BEFREE To evaluate if the presence of CNVs in the 22q11.2 region, and to determine whether GATA4, NKX2-5, TBX5, BMP, and CRELD1 genes contributed toward the pathogenesis of isolated incidences of CHDs in southwest China. 30221396 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 Biomarker disease BEFREE Germline mutations in the NKX2-5, GATA4, and CRELD1 genes do not appear to be associated with CHD in Mexican DS patients. 25524324 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 Biomarker disease BEFREE Crossing loss-of-function alleles of either Creld1 or Hey2 onto the trisomic background caused a significant increase in the frequency of CHD, demonstrating an interaction between the modifiers and trisomic genes. 22523272 2012
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 GeneticVariation disease BEFREE Therefore, the SNP c.985 C>T of CRELD1 is involved in causing CHD in patients of Mysore, South India. 21413875 2011