|
Nephrotic Syndrome
|
0.300 |
Biomarker
|
group |
GENOMICS_ENGLAND |
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
|
30179222 |
2018 |
|
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE
|
0.300 |
GermlineCausalMutation
|
disease |
ORPHANET |
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
|
30179222 |
2018 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
MICROCEPHALY 24, PRIMARY, AUTOSOMAL RECESSIVE
|
0.100 |
GeneticVariation
|
disease |
CLINVAR |
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
|
30179222 |
2018 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
|
25429064 |
2015 |
|
Narcolepsy
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association database developed in the Japanese Integrated Database Project.
|
19629137 |
2009 |
|
Microcephaly
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Cerebellar vermis hypoplasia
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Clinodactyly of the 5th finger
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
The results suggest that mycoplasma infection promotes tumor progression in HCC patients via interaction of the mycoplasmal p37 and EpCAM.
|
30980864 |
2019 |
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
Correction: Mapping of a Mycoplasma-Neutralizing Epitope on the Mycoplasmal p37 Protein.
|
28196145 |
2019 |
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
Identification of specific B cell linear epitopes of mycoplasma hyorhinis P37 protein using monoclonal antibodies against baculovirus-expressed P37 protein.
|
31690259 |
2019 |
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
These results suggest that mycoplasma induces a resistance to multiple drugs in hepatocarcinoma cells which required the interaction of P37 and Annexin A2.
|
28976984 |
2017 |
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
Previously, we generated 6 monoclonal antibodies (MAbs) against the mycoplasmal protein p37 and showed the presence of mycoplasma-infected circulating tumor cells in the blood of hepatocellular carcinoma patients by using CA27, one of the six MAbs.
|
28036384 |
2016 |
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
Our previous work showed that Mycoplasma hyorhinis (M. hyorhinis) infection was mediated by the interaction between p37 of M. hyorhinis and Annexin A2 (ANXA2) of host cells, however the translational value of this mechanism was unknown.
|
26812398 |
2016 |
|
Mycoplasma Infections
|
0.070 |
Biomarker
|
group |
BEFREE |
The infection of mycoplasma hyorhinis may contribute to the development of gastric cancer and Mycoplasma hyorhinis-induced malignant phenotypes were possibly mediated by p37.
|
21062494 |
2010 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
The mycoplasmal membrane protein p37 showed significant correlations with higher histologic stages and vascular invasion and predicted poor disease-free survival of HCC patients. p37-positive CTCs were detected in 42 out of 47 HCC patients (89%). p37-positive circulating cells were also detected in 4 out of 10 healthy donors (40%), and all were epithelial cell adhesion molecule (EpCAM)-positive.
|
30980864 |
2019 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
NUP37, a positive regulator of YAP/TEAD signaling, promotes the progression of hepatocellular carcinoma.
|
29228669 |
2017 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
These results suggest that mycoplasma induces a resistance to multiple drugs in hepatocarcinoma cells which required the interaction of P37 and Annexin A2.
|
28976984 |
2017 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Previously, we generated 6 monoclonal antibodies (MAbs) against the mycoplasmal protein p37 and showed the presence of mycoplasma-infected circulating tumor cells in the blood of hepatocellular carcinoma patients by using CA27, one of the six MAbs.
|
28036384 |
2016 |
|
Lyme Disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
Recombinant P37 may be a useful component of a set of defined antigens for the serodiagnosis of early Lyme disease.
|
9986810 |
1999 |
|
Lyme Disease
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
These data show that ospA is repressed while p35 and p37 are induced in human infection; these results are the first direct demonstration of differential B. burgdorferi gene expression during Lyme disease.
|
9806060 |
1998 |
|
Lyme Disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
The use of in vivo-expressed antigens such as P35 and P37 represents a new approach for Lyme disease serodiagnosis and for understanding the role of B. burgdorferi-specific immune responses in host immunity.
|
9175831 |
1997 |
|
Schizophrenia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Transcripts encoding 5' UTRs -2A and alternative exon -1 (Alt1), P37 and AS1 and AS2 were increased in SZ.
|
31211828 |
2019 |
|
Tumor Progression
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The results suggest that mycoplasma infection promotes tumor progression in HCC patients via interaction of the mycoplasmal p37 and EpCAM.
|
30980864 |
2019 |