|
Renal Cell Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
|
22138691 |
2011 |
|
Liver Cirrhosis, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Systems level analysis and identification of pathways and networks associated with liver fibrosis.
|
25380136 |
2014 |
|
Chloracne
|
0.300 |
Biomarker
|
disease |
CTD_human |
Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.
|
17101203 |
2007 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
|
22138691 |
2011 |
|
Chromophobe Renal Cell Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
|
22138691 |
2011 |
|
Sarcomatoid Renal Cell Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
|
22138691 |
2011 |
|
Collecting Duct Carcinoma of the Kidney
|
0.300 |
Biomarker
|
disease |
CTD_human |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
|
22138691 |
2011 |
|
Papillary Renal Cell Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
|
22138691 |
2011 |
|
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
|
Malignant neoplasm of breast
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we demonstrated that AHNAK mRNA levels were down-regulated in 7 out of 8 human breast cancer cell lines, especially in triple - negative breast cancer (TNBC) cell lines.
|
28494797 |
2017 |
|
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
The role of AHNAK in the cellular response of breast cancer cells to doxorubicin was also investigated.
|
29309757 |
2018 |
|
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
AHNAK is known to be a tumor suppressor in breast cancer due to its ability to activate the TGFβ signaling pathway.
|
29724814 |
2018 |
|
Breast Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
AHNAK is known to be a tumor suppressor in breast cancer due to its ability to activate the TGFβ signaling pathway.
|
29724814 |
2018 |
|
Breast Carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we demonstrated that AHNAK mRNA levels were down-regulated in 7 out of 8 human breast cancer cell lines, especially in triple - negative breast cancer (TNBC) cell lines.
|
28494797 |
2017 |
|
Breast Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
The role of AHNAK in the cellular response of breast cancer cells to doxorubicin was also investigated.
|
29309757 |
2018 |
|
Rheumatoid Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Immunoreactivity against an in vitro translated human AHNAK fragment was detected in 4.6% (5/109) of patients with rheumatoid arthritis, 29.5% (18/61) of patients with systemic lupus erythematosus (SLE), and 1.2% (2/172) of blood donors.
|
11866458 |
2002 |
|
Asthma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These analyses suggested that SNPs in the AHNAK and MS4A2 genes were indirectly associated with asthma.
|
22432035 |
2012 |
|
Cat-Scratch Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
The present study evaluated the role of AHNAK in Bartonella henselae infection.
|
30940323 |
2019 |
|
Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Finally, we identified AHNAK which is discussed as a tumor suppressor as the first paucimannose-carrying protein in glioblastoma and show the involvement of AHNAK in the observed paucimannose-dependent effects.
|
31320997 |
2019 |
|
Glioma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We found that the mRNA levels of AHNAK were down-regulated in 4 of 6 human glioma cell lines, especially in U87 and U251 cell lines.
|
28928883 |
2017 |
|
Hepatitis B
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
Our results revealed that AHNAK methylation level in peripheral blood decreases with the progression of hepatitis B-related liver disease.
|
30259695 |
2018 |
|
Lupus Erythematosus, Systemic
|
0.010 |
Biomarker
|
disease |
BEFREE |
Anti-AHNAK positive SLE patients had a higher frequency of homogeneous antinuclear antibody staining patterns and a lower frequency of recent mucosal ulcerations.
|
11866458 |
2002 |
|
melanoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
This is the first report that we are aware of which correlates a loss of AHNAK with melanoma and poor patient outcome.
|
26672724 |
2016 |
|
Mesothelioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Since AHNAK is involved in cell migration and invasion in other metastatic tumor cells, we conducted migration and invasion assays in mesothelioma cell lines.
|
24253341 |
2014 |
|
Androgen-Insensitivity Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Moreover, the major differential plasma proteins related to AIS were Fibronectin 1 (FN1), voltage-dependent anion channel 1 (VDAC1), Ras homolog family member A (RHOA), and AHNAK nucleoprotein (AHNAK).
|
30481617 |
2019 |