WDR77, WD repeat domain 77, 79084

N. diseases: 31; N. variants: 0
Disease: Prostate carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.050 AlteredExpression disease BEFREE Expression of PRMT5 and p44 in lung and prostate cancer cells was silenced and their target genes were identified. 27480244 2016
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.050 Biomarker disease BEFREE Cell proliferation assays with N- and C- terminal deletion mutations indicated that the central portion of p44 is required for nuclear p44 mediated prostate cancer growth inhibition. 23734213 2013
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.050 AlteredExpression disease BEFREE In contrast to findings in prostate cancer, the expression of p44 shows strong cytoplasmic expression in morphologically normal terminal ductal lobular units, while nuclear p44 is observed in both ductal carcinoma in situ and invasive carcinoma. 19840198 2010
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.050 Biomarker disease BEFREE Our results indicate that nuclear p44 and cytoplasmic p44 have distinct and opposing functions in the regulation of prostate cancer cell proliferation. 18356297 2008
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.050 Biomarker disease BEFREE The forced nuclear localization of p44 inhibited prostate cancer cell growth by G1 cell-cycle arrest. 17032745 2006