PLA2G7, phospholipase A2 group VII, 7941

N. diseases: 136; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.430 Biomarker disease BEFREE Among these PAF-AHs, plasma PAF-AH has been the target of many clinical studies in inflammatory diseases, such as asthma, sepsis, and vascular diseases, because the plasma PAF-AH activity in the patients with these diseases is altered when compared with normal individuals. 12547653 2003
CUI: C0004096
Disease: Asthma
Asthma
0.430 GeneticVariation disease BEFREE PAF acetylhydrolase gene polymorphisms and asthma severity. 11535107 2001
CUI: C0004096
Disease: Asthma
Asthma
0.430 Biomarker disease CTD_human The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma. 10733466 2000
CUI: C0004096
Disease: Asthma
Asthma
0.430 GeneticVariation disease BEFREE We conclude that the PAF acetylhydrolase gene is a modulating locus for the severity of asthma. 10194471 1999
CUI: C0004096
Disease: Asthma
Asthma
0.430 Biomarker disease HPO