PLA2G7, phospholipase A2 group VII, 7941

N. diseases: 136; N. variants: 11
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.220 GeneticVariation disease BEFREE Carriage of the V279F homozygous genotype, a rare allele, within the gene encoding Lp-PLA2 leads to changes in circulating intermediate metabolites in individuals without metabolic syndrome. 25078067 2014
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.220 Biomarker disease RGD The metabolic cascade leading to eicosanoid precursors--desaturases, elongases, and phospholipases A2--is altered in Zucker fatty rats. 21172452 2011
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.220 AlteredExpression disease BEFREE Lp-PLA2 activity is an independent predictor of CHD risk and MS in a sample of subjects with diabetes mellitus. 16438975 2006