Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 GeneticVariation disease BEFREE To clarify the relationship between STSS and pharyngitis in Japan, we examined the T serotypes of GAS strains isolated from clinical specimens of streptococcal infections (STSS, 951 isolates; pharyngitis, 16268 isolates) from 2005 to 2017. 31735631 2020
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE <i>Streptococcus pyogenes</i> (group A streptococcus [GAS]) is a serious human pathogen with the ability to colonize mucosal surfaces such as the nasopharynx and vaginal tract, often leading to infections such as pharyngitis and vulvovaginitis. 31239377 2019
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE <b>IMPORTANCE</b> The human bacterial pathogen <i>Streptococcus pyogenes</i> (group A streptococcus [GAS]) causes more than 600 million cases of pharyngitis annually worldwide, 15 million of which occur in the United States. 29104937 2019
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Based on our pragmatic trial, the routine use of this probiotic in the prevention of pharyngitis associated with GAS detection is not supported. 29189607 2018
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE A total of 135 GAS clinical strains were isolated from the tonsils of 116 pediatric patients with acute GAS pharyngitis between November, 2012 and April, 2014 in Saga, Japan. 30247119 2018
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 GeneticVariation disease BEFREE <i>Streptococcus pyogenes</i> (Group A <i>Streptococcus</i>; GAS) commonly causes pharyngitis in children and adults, with severe invasive disease and immune sequelae being an infrequent consequence. 29868516 2018
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Streptococcus pyogenes (group A Streptococcus, GAS) is responsible for a variety of highly communicable infections, accounting for 5-15 and 20-30% of sore throat hospital visits in adults and children, respectively. 29967988 2018
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. 28355251 2017
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE The case demonstrates that ARF can develop in the absence of GAS pharyngitis and highlights a need for further research into the role of pyoderma and non-Group A Streptococci infections in ARF pathogenesis. 28121967 2017
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Primary abscess of the iliopsoas muscle in children is uncommon, especially due to Streptococcus pyogenes (group A streptococcus: GAS), which causes a variety of diseases ranging from pharyngitis to invasive life-threatening infection. 27692341 2016
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE S. pyogenes (group A streptococcus [GAS]) causes pharyngitis ("strep throat"), necrotizing fasciitis, and other human infections. 26443457 2015
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE In this study, we investigate the role of zinc efflux in the pathogenesis of Streptococcus pyogenes (group A Streptococcus [GAS]), a human pathogen responsible for superficial infections, such as pharyngitis and impetigo, and severe invasive infections. 24449444 2014
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Rapid accurate detection of GAS in pharyngeal specimens from individuals suffering from pharyngitis aids in the management and selection of antibiotic therapy for these patients. 23447639 2013
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE This novel activity of NADase to block autophagic killing of GAS in pharyngeal cells may contribute to pharyngitis treatment failure, relapse, and chronic carriage. 23762025 2013
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Diseases caused by Streptococcus pyogenes (Group A streptococcus, GAS) range from superficial infections such as pharyngitis and impetigo to potentially fatal rheumatic heart disease and invasive disease. 23179674 2013
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 AlteredExpression disease BEFREE This in vivo genome-wide analysis of GAS gene expression in humans with pharyngitis evaluated global gene expression in terms of virulence factors. 21799202 2011
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE Streptococcus pyogenes (group A streptococci; GAS) recovered from paediatric pharyngitis (101 isolates) and asymptomatic children (79 isolates) in the same geographical area and period, as well as isolates collected during an enhanced national surveillance programme for GAS invasive diseases (79 isolates), were screened for the incidence of the streptococcal pyrogenic exotoxin (spe) genes speA and speC, as well as the macrolide-resistance genes erm(B), erm(A) subclass erm(TR) and mef(A), and typed by emm sequencing. 16157543 2005
CUI: C0031350
Disease: Pharyngitis
Pharyngitis
0.100 Biomarker disease BEFREE To provide new information about GAS host-pathogen interactions, we used real-time reverse transcription-PCR (RT-PCR) to analyze transcripts of 17 GAS genes in throat swab specimens taken from 18 pediatric patients with pharyngitis. 12654842 2003