|
Global developmental delay
|
0.300 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.
|
31587868 |
2019 |
|
Intellectual Disability
|
0.300 |
Biomarker
|
group |
GENOMICS_ENGLAND |
Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.
|
31587868 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
These data suggest that NKAP functions as an oncogene in the growth and invasion of colon cancer in vitro.
|
31545474 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Downregulation of NKAP in gliomas had abrogated tumor growth and invasion in vitro and in vivo.
|
31277684 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
In addition, knockdown of NKAP could strongly inhibit the migration and invasion of MCF-7 cells.
|
30464609 |
2018 |
|
Malignant tumor of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
These data suggest that NKAP functions as an oncogene in the growth and invasion of colon cancer in vitro.
|
31545474 |
2019 |
|
Glioma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression of NKAP and Notch1 in glioma and normal human brain samples were analyzed by immunohistochemical analysis.
|
31277684 |
2019 |
|
Lymphopenia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Previous studies demonstrated that the loss of NKAP, a transcriptional regulator of T cell maturation, caused peripheral T cell lymphopenia and enhanced complement susceptibility.
|
31175160 |
2019 |
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In the present study, we aimed to investigate the effect of NKAP on the progression and metastasis of colon cancer.
|
31545474 |
2019 |
|
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Interestingly, compared to the control group, inhibiting NKAP set up obstacles to tumor-associated macrophage (TAM) polarization and recruitment by decreasing the secretion of SDF-1 and M-CSF.
|
31277684 |
2019 |
|
Impaired cognition
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.
|
31587868 |
2019 |
|
Ewings sarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
NKAP was knocked-down in human ES cell lines A673 and RD-ES using small interfering (si)RNA transfection.
|
31555387 |
2019 |
|
Colon Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
These data suggest that NKAP functions as an oncogene in the growth and invasion of colon cancer in vitro.
|
31545474 |
2019 |
|
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
NKAP was differentially expressed in breast cancer and normal tissues and is a potential prognostic indicator of breast cancer.
|
30464609 |
2018 |
|
Breast Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
NKAP was differentially expressed in breast cancer and normal tissues and is a potential prognostic indicator of breast cancer.
|
30464609 |
2018 |
|
Liver carcinoma
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.
|
29353445 |
2018 |
|
Rheumatoid Arthritis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis.
|
23223422 |
2013 |