Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE In conclusion, TIPE2 could regulate the proliferation, migration, and invasion of human rectal adenocarcinoma cells through Wnt/β-Catenin and TGF-β/Smad2/3 signalling pathways. 30637920 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Adenovirus-mediated TIPE2 overexpression suppressed cell proliferation and invasion, and induced apoptosis in esophageal carcinoma cells. 29343267 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE TIPE2 markedly suppressed the viability, colony formation, migration and invasion of GIST cells. 30534358 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE TIPE2 overexpression significantly suppressed the viability, proliferation, migration and invasion of PTC cells. 30186591 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Wound healing and Transwell invasion assays showed that forced expression of TIPE2 markedly suppressed the gastric cancer cell migration and invasion in vitro. 26530498 2016
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE TIPE2 overexpression significantly inhibited hypoxia-induced migration and invasion, as well as suppressed the EMT process in glioma cells. 27656836 2016
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE In conclusion, for the first time we demonstrated that TIPE2 overexpression may suppress proliferation, migration, and invasion in prostate cancer cells by inhibiting the PI3K/Akt signaling pathway. 27712587 2016